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Date Issuer Insider Transaction Amount New Balance ⓘ
The balance of securities held by registered holder at the time of the transaction. Insiders may direct multiple registered holders and hold multiple security types.
Filed 2022-04-06 10:48
Tx date 2022-03-31
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
10 - Acquisition or disposition in the public market
$-56,280
-469,000 vol
$0.12 each
5,711,000
Filed 2022-04-06 10:48
Tx date 2022-03-30
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
10 - Acquisition or disposition in the public market
$-20,280
-156,000 vol
$0.13 each
6,180,000
Filed 2022-04-06 10:47
Tx date 2022-03-29
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
10 - Acquisition or disposition in the public market
$-37,245
-286,500 vol
$0.13 each
6,336,000
Filed 2022-04-06 10:47
Tx date 2022-03-28
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
10 - Acquisition or disposition in the public market
$-20,865
-160,500 vol
$0.13 each
6,622,500
Filed 2022-04-06 10:46
Tx date 2022-03-25
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
10 - Acquisition or disposition in the public market
$-13,200
-110,000 vol
$0.12 each
6,783,000
Filed 2022-04-06 10:45
Tx date 2022-03-24
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
10 - Acquisition or disposition in the public market
$-4,355
-33,500 vol
$0.13 each
6,893,000
Filed 2022-04-06 10:45
Tx date 2022-03-23
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
10 - Acquisition or disposition in the public market
$-13,000
-100,000 vol
$0.13 each
6,926,500
Filed 2022-04-06 10:44
Tx date 2022-03-23
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
10 - Acquisition or disposition in the public market
$-280.00
-2,000 vol
$0.14 each
7,026,500
Filed 2022-04-06 10:44
Tx date 2022-03-22
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
10 - Acquisition or disposition in the public market
$-9,600
-64,000 vol
$0.15 each
7,028,500
Filed 2022-04-06 10:43
Tx date 2022-03-21
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
10 - Acquisition or disposition in the public market
$-1,050
-7,000 vol
$0.15 each
7,092,500
Filed 2022-04-06 10:42
Tx date 2022-03-18
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
10 - Acquisition or disposition in the public market
$-1,840
-11,500 vol
$0.16 each
7,099,500
Filed 2022-04-06 10:41
Tx date 2022-03-16
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
10 - Acquisition or disposition in the public market
$-5,440
-32,000 vol
$0.17 each
7,111,000
Filed 2022-02-08 14:26
Tx date 2021-02-19
$PSYB
PsyBio Therapeutics Corp. (formerly Leo Acquisitions Corp.)
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Genesis Master Fund, L.P. (Control or Direction)
Subordinate Voting Shares
00 - Opening Balance-Initial SEDI Report
7,143,000
Filed 2020-11-17 12:29
Tx date 2020-03-03
$HLS
HLS Therapeutics Inc.
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-762,356.30
-47,030 vol
$16.21 each
605,598
Filed 2020-11-17 12:28
Tx date 2020-02-27
$HLS
HLS Therapeutics Inc.
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-3,658.95
-235 vol
$15.57 each
652,628
Filed 2020-11-17 12:28
Tx date 2020-03-03
$HLS
HLS Therapeutics Inc.
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-2,286,906.80
-141,080 vol
$16.21 each
1,816,803
Filed 2020-11-17 12:27
Tx date 2020-02-27
$HLS
HLS Therapeutics Inc.
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-10,992.42
-706 vol
$15.57 each
1,957,883
Filed 2020-11-17 12:26
Tx date 2020-03-03
$HLS
HLS Therapeutics Inc.
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-192,736.90
-11,890 vol
$16.21 each
51,214
Filed 2020-11-17 12:24
Tx date 2020-02-27
$HLS
HLS Therapeutics Inc.
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-918.63
-59 vol
$15.57 each
63,104
Filed 2020-11-17 12:21
Tx date 2020-08-11
$HLS
HLS Therapeutics Inc.
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Warrants
55 - Expiration of warrants

-63,193 vol
135,836
Filed 2020-11-17 12:21
Tx date 2020-08-11
$HLS
HLS Therapeutics Inc.
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Warrants
55 - Expiration of warrants

-189,578 vol
407,507
Filed 2020-11-17 12:20
Tx date 2020-08-11
$HLS
HLS Therapeutics Inc.
OrbiMed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Warrants
55 - Expiration of warrants

-63,193 vol
135,836
Filed 2020-06-15 09:32
Tx date 2020-06-09
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-1,522,468
-148,100 vol
$10.28 each
4,795,316
Filed 2020-06-15 09:31
Tx date 2020-06-10
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-366,184
-36,400 vol
$10.06 each
1,182,416
Filed 2020-06-15 09:26
Tx date 2020-06-10
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-366,184
-36,400 vol
$10.06 each
Filed 2020-06-15 09:25
Tx date 2020-06-10
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-7,009,000
-700,900 vol
$10.00 each
1,218,816
Filed 2020-06-15 09:24
Tx date 2020-06-10
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-7,991,000
-799,100 vol
$10.00 each
3,954,800
Filed 2020-06-15 09:23
Tx date 2020-06-10
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-416,644.96
-41,416 vol
$10.06 each
4,753,900
Filed 2020-06-15 09:22
Tx date 2020-06-09
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-1,672,556
-162,700 vol
$10.28 each
1,919,716
Filed 2020-06-15 09:21
Tx date 2020-06-09
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-1,522,468
-148,100 vol
$10.28 each
Filed 2020-01-07 17:15
Tx date 2020-01-02
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Warrants
54 - Exercise of warrants
$-568.728
-63,192 vol
$0.009 each
199,029
Filed 2020-01-07 17:13
Tx date 2020-01-02
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Common Shares
54 - Exercise of warrants
$568.47
+63,163 vol
$0.009 each
652,863
Filed 2020-01-07 17:12
Tx date 2020-01-02
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Warrants
54 - Exercise of warrants
$-1,706.184
-189,576 vol
$0.009 each
597,085
Filed 2020-01-07 17:10
Tx date 2020-01-02
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Common Shares
54 - Exercise of warrants
$1,705
+189,489 vol
$0.009 each
1,958,589
Filed 2020-01-07 17:07
Tx date 2020-01-02
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Warrants
54 - Exercise of warrants
$-568.728
-63,192 vol
$0.009 each
199,029
Filed 2020-01-07 17:06
Tx date 2020-01-02
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
54 - Exercise of warrants
$568.47
+63,163 vol
$0.009 each
63,163
Filed 2019-12-20 16:12
Tx date 2019-12-17
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$-4,191,400
-220,600 vol
$19.00 each
2,138,210
Filed 2019-12-20 16:11
Tx date 2019-12-18
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$-7,105,367.50
-369,110 vol
$19.25 each
1,769,100
Filed 2019-12-20 16:10
Tx date 2019-12-18
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$-2,369,213
-123,076 vol
$19.25 each
589,700
Filed 2019-12-20 16:10
Tx date 2019-12-18
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$-1,102,062.50
-57,250 vol
$19.25 each
0
Filed 2019-12-20 16:09
Tx date 2019-12-17
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$-1,396,500
-73,500 vol
$19.00 each
712,776
Filed 2019-12-20 16:08
Tx date 2019-12-17
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$-112,100
-5,900 vol
$19.00 each
57,250
Filed 2019-12-20 16:07
Tx date 2019-12-17
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$-1,522.40
-80 vol
$19.03 each
2,358,810
Filed 2019-12-20 16:06
Tx date 2019-12-17
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$-380.60
-20 vol
$19.03 each
786,276
Filed 2019-11-20 17:54
Tx date 2019-11-15
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Common Shares
54 - Exercise of warrants
$568.35
+63,150 vol
$0.009 each
786,296
Filed 2019-11-20 17:53
Tx date 2019-11-15
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Warrants
54 - Exercise of warrants
$-568.728
-63,192 vol
$0.009 each
262,221
Filed 2019-11-20 17:51
Tx date 2019-11-15
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Common Shares
54 - Exercise of warrants
$1,705
+189,450 vol
$0.009 each
2,358,890
Filed 2019-11-20 17:50
Tx date 2019-11-15
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Warrants
54 - Exercise of warrants
$-1,706.184
-189,576 vol
$0.009 each
786,661
Filed 2019-11-20 17:47
Tx date 2019-11-15
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
54 - Exercise of warrants
$568.35
+63,150 vol
$0.009 each
63,150
Filed 2019-11-20 17:46
Tx date 2019-11-15
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Warrants
54 - Exercise of warrants
$-568.728
-63,192 vol
$0.009 each
262,221
Filed 2019-11-20 17:45
Tx date 2019-11-15
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Warrants
54 - Exercise of warrants
$-568.728
-63,192 vol
$0.009 each
Filed 2019-11-20 17:44
Tx date 2019-11-15
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Warrants
54 - Exercise of warrants
$-568.728
-63,192 vol
$0.009 each
Filed 2019-11-20 17:43
Tx date 2019-11-15
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
54 - Exercise of warrants
$568.35
+63,150 vol
$0.009 each
Filed 2019-11-20 17:43
Tx date 2019-11-15
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
54 - Exercise of warrants
$568.35
+63,150 vol
$0.009 each
Filed 2019-11-20 17:41
Tx date 2019-11-15
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
54 - Exercise of warrants
$568.35
+63,150 vol
$0.009 each
Filed 2019-11-20 17:37
Tx date 2019-11-15
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Warrants
54 - Exercise of warrants
$-568.728
-63,192 vol
$0.009 each
Filed 2019-09-06 16:32
Tx date 2019-09-05
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Control or Direction)
Common Shares
15 - Acquisition or disposition under a prospectus
$1,988,000
+280,000 vol
$7.10 each
4,943,416
Filed 2019-09-06 16:32
Tx date 2019-08-15
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Control or Direction)
Common Shares
37 - Stock split or consolidation

-12,124,884 vol
4,663,416
Filed 2019-09-06 16:27
Tx date 2019-09-05
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
15 - Acquisition or disposition under a prospectus
$2,982,000
+420,000 vol
$7.10 each
2,082,416
Filed 2019-09-06 16:26
Tx date 2019-08-15
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
37 - Stock split or consolidation

-4,322,284 vol
1,662,416
Filed 2019-09-06 16:21
Tx date 2019-09-05
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-9,087,457.50
-673,145 vol
$13.50 each
0
Filed 2019-08-21 18:28
Tx date 2019-08-16
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$-700,000
-50,000 vol
$14.00 each
673,145
Filed 2019-08-21 18:27
Tx date 2019-04-03
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Common Shares
54 - Exercise of warrants
$1,894
+189,440 vol
$0.01 each
2,169,440
Filed 2019-08-21 18:26
Tx date 2019-04-03
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Common Shares
54 - Exercise of warrants
$631.46
+63,146 vol
$0.01 each
723,146
Filed 2019-08-21 18:24
Tx date 2019-04-03
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
54 - Exercise of warrants
$631.46
+63,146 vol
$0.01 each
723,145
Filed 2019-08-21 18:23
Tx date 2019-04-03
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Warrants
54 - Exercise of warrants
$-1,895.76
-189,576 vol
$0.01 each
976,237
Filed 2019-08-21 18:19
Tx date 2019-04-03
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Warrants
54 - Exercise of warrants
$-631.92
-63,192 vol
$0.01 each
325,413
Filed 2019-08-21 18:18
Tx date 2019-04-03
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Warrants
54 - Exercise of warrants
$-631.92
-63,192 vol
$0.01 each
325,413
Filed 2019-08-21 18:17
Tx date 2019-04-03
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Warrants
54 - Exercise of warrants
$-631.92
-63,192 vol
$0.01 each
Filed 2019-08-21 18:17
Tx date 2019-08-03
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Warrants
54 - Exercise of warrants
$-631.92
-63,192 vol
$0.01 each
Filed 2019-08-21 18:16
Tx date 2019-04-03
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Warrants
54 - Exercise of warrants
$-631.92
-63,192 vol
$0.01 each
Filed 2019-08-21 18:15
Tx date 2019-08-03
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Warrants
54 - Exercise of warrants
$-631.92
-63,192 vol
$0.01 each
Filed 2019-08-21 18:14
Tx date 2019-04-03
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Warrants
54 - Exercise of warrants
$-631.92
-63,192 vol
$0.01 each
Filed 2019-08-21 18:13
Tx date 2019-08-03
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Warrants
54 - Exercise of warrants
$-631.92
-63,192 vol
$0.01 each
Filed 2019-05-12 14:00
Tx date 2019-05-10
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$284,000
+200,000 vol
$1.42 each
16,788,300
Filed 2019-05-12 13:59
Tx date 2019-05-09
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$200,513
+145,300 vol
$1.38 each
16,588,300
Filed 2019-05-12 13:59
Tx date 2019-05-08
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$435,780
+322,800 vol
$1.35 each
16,443,000
Filed 2019-05-12 13:58
Tx date 2019-05-07
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Control or Direction)
Common Shares
10 - Acquisition or disposition in the public market
$977,358
+794,600 vol
$1.23 each
16,120,200
Filed 2019-05-12 13:57
Tx date 2019-05-10
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$284,000
+200,000 vol
$1.42 each
Filed 2019-05-12 13:57
Tx date 2019-05-09
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$200,513
+145,300 vol
$1.38 each
Filed 2019-05-12 13:57
Tx date 2019-05-08
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$435,780
+322,800 vol
$1.35 each
Filed 2019-05-12 13:56
Tx date 2019-05-07
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$977,358
+794,600 vol
$1.23 each
Filed 2019-05-12 13:56
Tx date 2019-05-10
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$284,000
+200,000 vol
$1.42 each
Filed 2019-05-12 13:55
Tx date 2019-05-09
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$200,513
+145,300 vol
$1.38 each
Filed 2019-05-12 13:55
Tx date 2019-05-08
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$435,780
+322,800 vol
$1.35 each
Filed 2019-05-12 13:54
Tx date 2019-05-07
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Indirect Ownership)
Common Shares
10 - Acquisition or disposition in the public market
$977,358
+794,600 vol
$1.23 each
Filed 2018-12-20
Tx date 2018-12-18
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Control or Direction)
Common Shares
00 - Opening Balance-Initial SEDI Report
2,625,800
Filed 2018-12-20
Tx date 2018-12-18
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments VII, LP (Control or Direction)
Common Shares
15 - Acquisition or disposition under a prospectus
$12,064,810
+12,699,800 vol
$0.95 each
15,325,600
Filed 2018-12-20
Tx date 2018-12-18
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
00 - Opening Balance-Initial SEDI Report
1,784,700
Filed 2018-12-20
Tx date 2018-12-18
$BLU
BELLUS Health Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
15 - Acquisition or disposition under a prospectus
$3,990,000
+4,200,000 vol
$0.95 each
5,984,700
Filed 2018-03-16
Tx date 2018-03-12
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Warrants
00 - Opening Balance-Initial SEDI Report
Filed 2018-03-16
Tx date 2018-03-12
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Common Shares
00 - Opening Balance-Initial SEDI Report
Filed 2018-03-16
Tx date 2018-03-12
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
00 - Opening Balance-Initial SEDI Report
Filed 2018-03-16
Tx date 2018-03-12
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Common Shares
22 - Acquisition or disposition pursuant to a take-over bid, merger or acquisition

+659,999 vol
659,999
Filed 2018-03-16
Tx date 2018-03-12
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Common Shares
22 - Acquisition or disposition pursuant to a take-over bid, merger or acquisition

+1,980,000 vol
1,980,000
Filed 2018-03-16
Tx date 2018-03-12
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Common Shares
00 - Opening Balance-Initial SEDI Report
Filed 2018-03-16
Tx date 2018-03-12
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Common Shares
22 - Acquisition or disposition pursuant to a take-over bid, merger or acquisition

+660,000 vol
660,000
Filed 2018-03-16
Tx date 2018-03-12
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Warrants
00 - Opening Balance-Initial SEDI Report
Filed 2018-03-16
Tx date 2018-03-12
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Partners Master Fund Limited (Control or Direction)
Warrants
22 - Acquisition or disposition pursuant to a take-over bid, merger or acquisition

+388,605 vol
388,605
Filed 2018-03-16
Tx date 2018-03-12
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Warrants
00 - Opening Balance-Initial SEDI Report
Filed 2018-03-16
Tx date 2018-03-12
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Royalty Opportunities II, LP (Control or Direction)
Warrants
22 - Acquisition or disposition pursuant to a take-over bid, merger or acquisition

+1,165,813 vol
1,165,813
Filed 2018-03-16
Tx date 2018-03-12
$HLS
HLS Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: Royalty Opportunities S.àr.l. (Control or Direction)
Warrants
22 - Acquisition or disposition pursuant to a take-over bid, merger or acquisition

+388,605 vol
388,605
Filed 2017-08-22
Tx date 2017-08-14
$CMTA
Clementia Pharmaceuticals Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments IV, LP (Control or Direction)
Common Shares
00 - Opening Balance-Initial SEDI Report
10,425,225
Filed 2016-09-09
Tx date 2016-09-06
$CTH
Cynapsus Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments V, LP (Indirect Ownership)
Common Shares
11 - Acquisition or disposition carried out privately
$-24,657,918.75
-620,325 vol
$39.75 each
1,000,000
Filed 2016-07-12
Tx date 2016-07-06
$CTH
Cynapsus Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments V, LP (Indirect Ownership)
Common Shares
00 - Opening Balance-Initial SEDI Report
Filed 2016-07-12
Tx date 2016-07-06
$CTH
Cynapsus Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments V, LP (Indirect Ownership)
Common Shares
00 - Opening Balance-Initial SEDI Report
1,620,325
Filed 2016-07-12
Tx date 2016-07-06
$CTH
Cynapsus Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments V, LP (Indirect Ownership)
Warrants
00 - Opening Balance-Initial SEDI Report
Filed 2016-07-12
Tx date 2016-07-06
$CTH
Cynapsus Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments V, LP (Indirect Ownership)
Common Shares
00 - Opening Balance-Initial SEDI Report
Filed 2016-07-12
Tx date 2016-07-06
$CTH
Cynapsus Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments V, LP (Indirect Ownership)
Warrants
00 - Opening Balance-Initial SEDI Report
Filed 2016-07-12
Tx date 2016-07-06
$CTH
Cynapsus Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments V, LP (Indirect Ownership)
Warrants
00 - Opening Balance-Initial SEDI Report
316,154
Filed 2016-07-12
Tx date 2016-07-06
$CTH
Cynapsus Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments V, LP (Indirect Ownership)
Warrants
00 - Opening Balance-Initial SEDI Report
Filed 2016-07-12
Tx date 2016-07-06
$CTH
Cynapsus Therapeutics Inc.
Orbimed Advisors LLC
3 - 10% Security Holder of Issuer
Holder: OrbiMed Private Investments V, LP (Indirect Ownership)
Common Shares
00 - Opening Balance-Initial SEDI Report